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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.22%⁩, the S&P 500 is ⁦+0.59%⁩, and the Nasdaq Composite is ⁦+1.34%⁩. Across individual stocks, 2,262 are advancing while 2,855 are declining, suggesting a mixed market tone.

Dow Jones
51,410.22
Change
-112.84-0.22%
S&P 500
7,396.85
Change
+43.12+0.59%
Nasdaq Composite
24,641.964
Change
+326.967+1.34%
24H Gainers
2,262
24H Losers
2,855

52 Week Gainers

#Stock52 Week Range
5051IP Strategy Holdings, Inc.IPST$2.15+0.23%9.65K$2.15M$1.54 - $301.600.00%
5052POMDOCTOR LIMITEDPOM$1.41-1.44%19.83K$4.11M$0.43 - $115.740.00%
5053Chanson International HoldingCHSN$2.80+12.77%298.48K$10.19M$0.70 - $331.000.00%
5054Mint Incorporation LimitedMIMI$0.96+9.90%900.98K$12.13M$0.61 - $76.800.00%
5055Lianhe Sowell International Group LtdLHSW$3.15-8.96%7.57K$5.63M$3.05 - $262.400.00%
5056LZ Technology Holdings LimitedLZMH$0.81+1.62%3.70K$6.38M$0.66 - $66.600.00%
5057GeoVax Labs, Inc. NewGOVX$0.15-2.53%55.17K$1.56M$0.14 - $13.530.00%
5058Meiwu Technology Company LimitedWNW$1.90+1.06%3.96K$50.03M$1.80 - $1,352.000.00%
5059Instinct Bio Technical Company Holdings Inc.BIOT$0.18-1.49%57.02K$5.34M$0.17 - $50.000.00%
5060Global Mofy AI LimitedGMM$1.01+0.92%7.78K$9.68M$0.83 - $92.500.00%
5061Treasure Global Inc.TGL$0.17-1.60%292.31K$897.82K$0.17 - $58.000.00%
5062SU Group Holdings LimitedSUGP$1.65+3.46%7.38K$444.09K$1.47 - $291.000.00%
5063Nexera Technologies LtdNEXR$1.89+2.16%234.80K$1.05M$0.55 - $299.190.00%
5064Baiya International Group Inc.BIYA$1.10+2.80%14.53K$2.93M$1.07 - $167.970.00%
5065Karyopharm Therapeutics Inc.KPTI$0.05-24.29%76.31M$1.07M$0.04 - $10.990.00%
5066Huachen AI Parking Management Technology Holding Co., Ltd.HCAI$2.91+1.75%6.40K$1.28M$2.01 - $519.800.00%
5067zSpace, Inc.ZSPC$0.000.00%0$0$0.05 - $24.700.00%
5068Diginex LimitedDGNX$1.21+3.91%53.80K$35.10M$0.85 - $169.200.00%
506920/20 Biolabs, Inc.AIDX$0.19-1.05%41.52K$3.00M$0.18 - $50.000.00%
5070GlucoTrack, Inc.GCTK$1.37-33.66%4.12M$0$0.34 - $207.000.00%
5071Sunshine Biopharma Inc.SBFM$2.79+2.38%5.71K$2.13M$2.53 - $464.000.00%
5072U Power LimitedUCAR$3.07+2.50%18.33K$5.43M$2.34 - $438.000.00%
5073Parabolic Technologies, Inc.PARA$0.13-19.21%15.90M$66.30K$0.13 - $19.400.00%
5074Wetour Robotics LimitedWETO$0.85+0.85%121.56K$911.82K$0.73 - $139.990.00%
5075T3 Defense Inc.DFNS$2.05-9.61%547.73K$6.90M$1.84 - $335.000.00%
5076VisionWave Holdings, Inc.VWAV$1.40-6.52%43.03K$5.80M$1.38 - $316.000.00%
5077Creative Media & Community Trust CorporationCMCT$3.60+0.70%102$9.93M$1.77 - $1,441.001.51%
5078Interactive Strength Inc.TRNR$1.13-3.42%5.26K$1.83M$1.13 - $205.940.00%
5079Propanc Biopharma, Inc.PPCB$1.71+0.59%2.55K$1.77M$1.63 - $315.000.00%
5080Onfolio Holdings Inc.ONFO$0.35-5.03%25.56K$872.24K$0.32 - $123.920.44%
5081Inno Holdings Inc.INHD$2.97+3.32%9.38K$7.50M$1.01 - $1,656.000.00%
5082Onconetix, Inc.ONCO$7.42+30.78%123.58K$43.66M$1.44 - $1,610.000.00%
5083Linkers Industries LimitedLNKS$0.58-1.88%16.71K$880.86K$0.56 - $420.000.00%
5084Nuwellis, Inc.NUWE$4.53-1.93%11.46K$2.40M$2.52 - $1,556.070.00%
5085Enlivex Ltd.ENLV$1.270.00%3.40K$1.95M$1.22 - $434.400.00%
5086Zhibao Technology Inc.ZBAO$0.24+5.42%136.93K$6.71M$0.22 - $67.000.00%
5087Silexion Therapeutics Corp.SLXN$0.15-3.29%25.50K$2.24M$0.14 - $32.380.00%
5088Functional Brands, Inc.MEHA$0.00-55.31%0$0$0.00 - $2.230.00%
5089Lakewood-Amedex Biotherapeutics Inc.LABT$0.38-28.71%23.59M$462.09K$0.17 - $98.200.00%
5090Freight Technologies, Inc.FRGT$0.94+4.34%47.24K$64.55K$0.79 - $342.500.00%
5091KALA BIO, Inc.KALA$0.16-0.85%86.75K$3.04M$0.11 - $95.500.00%
5092Top Wealth Group Holding LimitedTWG$2.48-6.84%12.08K$1.98M$2.44 - $2,636.000.00%
5093NETCLASS TECHNOLOGY INC.NTCL$0.23-14.91%3.51M$295.42K$0.21 - $155.000.00%
5094Lucas GC LimitedLGCL$1.44+11.63%27.82K$1.65M$1.07 - $372.500.00%
5095Elme CommunitiesELME$0.07-96.19%235.55M$5.99M$0.06 - $17.680.00%
5096DarkIris Inc.DKI$1.60-2.71%115.47K$89.90K$1.33 - $968.000.00%
5097Wellchange Holdings Company LimitedWCT$0.23-1.68%45.72K$3.80M$0.23 - $67.500.00%
5098Fitness Champs Holdings LimitedFCHL$0.69+2.80%5.34K$1.11M$0.52 - $193.500.00%
5099SmartKem, Inc.SMTK$0.29-1.36%55.51K$301.42K$0.23 - $100.000.00%
5100Stardust Power Inc.SDST$0.01-30.11%147.33M$0$0.00 - $4.870.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
IP Strategy Holdings, Inc. (IPST) currently leads with a 52-week gain of 98.71% as of 2026-11-06 20:00 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.