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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.15%⁩, the S&P 500 is ⁦+0.65%⁩, and the Nasdaq Composite is ⁦+1.39%⁩. Across individual stocks, 2,299 are advancing while 2,818 are declining, suggesting a mixed market tone.

Dow Jones
51,444.97
Change
-78.09-0.15%
S&P 500
7,401.76
Change
+48.03+0.65%
Nasdaq Composite
24,653.757
Change
+338.76+1.39%
24H Gainers
2,299
24H Losers
2,818

52 Week Gainers

#Stock52 Week Range
4951Children's Place, Inc.PLCE$0.37+12.44%7.56M$8.23M$0.20 - $9.560.00%
4952Aptevo Therapeutics Inc.APVO$1.22-4.72%30.26K$2.21M$1.07 - $28.080.00%
4953Rich Sparkle Holdings LimitedANPA$1.19-0.83%11.43K$18.35M$1.14 - $180.640.00%
4954BNB Plus Corp.BNBX$0.16-58.08%4.55M$0$0.07 - $3.590.00%
4955Jyong Biotech Ltd.MENS$1.69+1.82%24.25K$128.49M$1.43 - $42.000.00%
4956FiscalNote Holdings, Inc.NOTE$0.000.00%0$0$0.00 - $3.490.00%
4957Decent Holding Inc.DXST$1.03-3.74%13.11K$2.24M$1.01 - $62.000.00%
4958Boxlight CorporationBOXL$1.90-1.78%12.34K$1.60M$1.80 - $50.760.00%
4959CXApp Inc.CXAI$1.35+12.61%106.94K$3.17M$1.12 - $33.000.00%
4960Ernexa Therapeutics Inc.ERNA$1.86+4.49%6.81K$3.04M$1.74 - $46.110.00%
4961Algorhythm Holdings, Inc.RIME$0.09+4.07%2.04M$1.47M$0.08 - $4.580.00%
4962Nocera, Inc.NCRA$1.40+3.63%5.39K$3.39M$1.29 - $40.500.00%
4963Vistagen Therapeutics, Inc.VTGN$0.17+1.88%360.22K$7.46M$0.17 - $5.140.00%
4964Arcadia Biosciences, Inc.RKDA$0.16+2.08%127.43K$390.29K$0.11 - $4.180.00%
4965Solmate Infrastructure Public Limited CompanySLMT$2.79+0.35%16.52K$23.40M$2.72 - $84.000.00%
4966Tenon Medical, Inc.TNON$1.64+1.22%62.59K$4.41M$1.60 - $45.500.00%
4967Innventure, Inc.INV$0.14-14.71%4.75M$11.80M$0.12 - $7.860.00%
4968Robo.ai Inc.AIIO$9.51-5.59%110.88K$2.11B$2.01 - $515.000.00%
4969Getty Images Holdings, Inc.GETY$0.08-40.95%27.99M$0$0.00 - $3.210.00%
4970Future FinTech Group Inc.FTFT$3.53-12.70%174.05K$30.61M$1.22 - $97.270.00%
4971Tempest Therapeutics, Inc.TPST$0.38+1.31%72.77K$7.66M$0.37 - $10.330.00%
4972Liminatus Pharma, Inc.LIMN$2.56-6.04%26.84K$3.75M$2.40 - $141.500.00%
4973Vivos Therapeutics, Inc.VVOS$0.09-9.75%649.72K$3.12M$0.09 - $2.720.00%
4974Maison Solutions Inc.MSS$1.06+12.13%93.56K$859.17K$0.94 - $30.500.00%
4975Powell Max LimitedPMAX$0.86+0.99%203.30K$1.13M$0.45 - $33.500.00%
4976Artelo Biosciences, Inc.ARTL$1.95-4.88%11.55K$1.07M$1.93 - $179.190.00%
4977Moleculin Biotech, Inc.MBRX$8.64-2.70%11.69K$8.46M$3.23 - $253.050.00%
4978Dogness (International) CorporationDOGZ$0.44-30.65%215.33K$3.77M$0.38 - $13.000.00%
4979Nexalin Technology, Inc.NXL$1.41-5.07%20.89K$1.61M$1.31 - $40.800.00%
4980Veraxa Biotech AGVRXA$0.93-0.36%126.28K$139.99M$0.90 - $27.360.00%
4981VS Media Holdings LimitedVSME$1.03+28.05%219.32K$4.69M$0.58 - $30.800.00%
4982GRI Bio, Inc.GRI$1.78+13.55%39.94K$3.90M$1.36 - $64.120.00%
4983Agroz Inc.AGRZ$1.91+2.98%7.48K$2.12M$1.73 - $105.680.00%
4984Pop Culture Group Co., LtdCPOP$3.00+5.07%4.80K$2.82M$2.47 - $382.500.00%
4985IceCure Medical Ltd.ICCM$0.72+2.71%29.85K$2.46M$0.65 - $22.500.00%
4986Cable One, Inc.CABO$4.56-12.18%338.78K$25.86M$4.04 - $145.220.00%
4987VenHub Global, Inc.VHUB$0.22-4.25%23.34K$22.92M$0.21 - $40.300.00%
49883 E Network Technology Group LtdMASK$1.95+2.38%89.20K$2.54M$1.50 - $66.530.00%
4989Triller Group Inc.ILLR$0.19-18.65%3.40M$0$0.01 - $7.960.00%
4990Trident Digital Tech Holdings LtdTDTH$0.60-6.56%14.80K$17.30M$0.56 - $21.000.00%
4991707 Cayman Holdings LimitedJEM$2.39+3.46%4.14K$1.58M$2.21 - $135.240.00%
4992MDxHealth SAMDXH$0.15+0.66%258.90K$15.11M$0.14 - $4.820.00%
4993Cloudastructure, Inc.CSAI$1.54-15.85%27.26K$1.34M$1.54 - $57.230.12%
4994EyePoint, Inc.EYPT$0.35-1.18%4.13M$30.61M$0.33 - $19.110.00%
4995iSpecimen Inc.ISPC$0.82+2.69%221.27K$2.06M$0.75 - $27.440.00%
4996BGM Group LtdBGM$8.80+3.51%880$111.62M$6.45 - $291.300.00%
4997Curis Inc.CRIS$0.90+4.13%2.32M$1.87M$0.33 - $29.800.00%
4998reAlpha Tech Corp.AIRE$0.39+1.84%44.76K$2.32M$0.32 - $16.200.00%
4999MKDWELL Tech Inc.MKDW$0.16-1.38%146.42K$5.61M$0.14 - $12.940.00%
5000Akanda Corp.AKAN$0.88+1.86%36.83K$2.09M$0.80 - $78.900.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Children's Place, Inc. (PLCE) currently leads with a 52-week gain of 95.39% as of 2026-11-06 20:00 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.