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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦-0.03%⁩, the S&P 500 is ⁦+0.79%⁩, and the Nasdaq Composite is ⁦+1.54%⁩. Across individual stocks, 2,326 are advancing while 2,791 are declining, suggesting a mixed market tone.

Dow Jones
51,507.85
Change
-15.21-0.03%
S&P 500
7,411.51
Change
+57.78+0.79%
Nasdaq Composite
24,689.228
Change
+374.231+1.54%
24H Gainers
2,326
24H Losers
2,791

52 Week Gainers

#Stock52 Week Range
51American Well CorporationAMWL$12.00-0.91%55.41K$180.73M$3.71 - $15.160.00%
52Micron Technology, Inc.MU$693.14+5.64%34.04M$784.23B$192.59 - $1,255.000.00%
53Eton Pharmaceutcials, Inc.ETON$55.12+16.74%810.07K$1.58B$14.27 - $66.370.00%
54Paysign, Inc.PAYS$14.63+2.03%435.88K$825.76M$3.08 - $16.150.00%
55Butterfly Network, Inc.BFLY$6.37+4.86%2.13M$1.57B$1.90 - $10.210.00%
56Bandwidth Inc.BAND$40.17+5.86%230.72K$1.22B$12.50 - $79.080.00%
57EuroDry LtdEDRY$35.28+0.99%32.98K$101.15M$12.30 - $73.070.00%
58Lindblad Expeditions Holdings Inc.LIND$33.59+6.10%384.77K$2.20B$11.37 - $38.850.00%
59Absci CorporationABSI$10.02+6.98%2.73M$1.72B$2.24 - $12.540.00%
60Relay Therapeutics, Inc.RLAY$18.10+5.94%1.56M$3.97B$5.95 - $21.270.00%
61Andersen Group Inc.ANDG$64.77-1.18%615.11K$1.22B$18.12 - $68.410.00%
62Glaukos CorporationGKOS$225.34+2.55%560.14K$13.34B$80.91 - $255.190.00%
63Vestis CorporationVSTS$14.38+1.98%351.53K$1.90B$5.00 - $16.900.00%
64Prelude Therapeutics IncorporatedPRLD$3.67+3.09%77.08K$292.48M$1.17 - $6.830.00%
65Tango Therapeutics, Inc.TNGX$21.54+3.31%682.90K$3.63B$7.37 - $34.390.00%
66RINGCENTRAL, INC.RNG$72.32-2.78%838.72K$5.40B$24.14 - $98.140.00%
67Immix Biopharma, Inc.IMMX$8.06+11.53%888.14K$576.61M$2.85 - $15.100.00%
68Agencia Comercial Spirits LtdAGCC$14.21+0.78%91.35K$597.30M$4.72 - $25.730.00%
69Septerna, Inc.SEPN$49.80+5.03%146.06K$2.04B$17.55 - $51.150.00%
70Maase Inc.MAAS$10.36+1.23%14.07K$4.51B$3.52 - $24.900.00%
71Enliven Therapeutics, Inc.ELVN$48.43+8.73%547.33K$3.55B$14.79 - $62.320.00%
72American Outdoor Brands, Inc.AOUT$17.45+1.54%52.69K$220.18M$6.26 - $19.500.00%
73FIGS, Inc.FIGS$19.73-2.70%4.03M$3.12B$7.31 - $22.460.00%
74QTREX Quantum Ltd.QTEX$1.02+9.42%1.75M$57.36M$0.28 - $3.850.00%
75Edgewise Therapeutics, Inc.EWTX$44.63+14.18%2.20M$4.85B$16.70 - $48.510.00%
76LB Pharmaceuticals Inc.LBRX$40.44+5.80%222.56K$1.30B$14.32 - $50.160.00%
77Iridium Communications Inc.IRDM$43.95+4.36%246.80K$4.67B$15.64 - $57.180.01%
78AbCellera Biologics Inc.ABCL$11.77+5.66%1.29M$3.61B$2.75 - $15.020.00%
79Sezzle Inc.SEZL$150.55-2.08%490.94K$5.09B$49.50 - $195.710.00%
80Hinge Health, Inc.HNGE$114.30-1.48%699.90K$9.43B$30.08 - $124.940.00%
81Xencor, Inc.XNCR$36.23+6.12%557.17K$2.69B$10.38 - $36.480.00%
82Maravai LifeSciences Holdings, Inc.MRVI$7.46+6.66%918.16K$1.11B$2.54 - $9.420.00%
83Hycroft Mining Holding CorporationHYMC$18.66+9.46%1.67M$1.74B$7.07 - $58.730.00%
84Alto Ingredients, Inc.ALTO$3.65-0.54%1.82M$282.73M$1.30 - $6.110.00%
85First Tracks Biotherapeutics, Inc.TRAX$47.20+3.83%259.79K$1.95B$14.72 - $50.170.00%
86Omeros CorporationOMER$16.67-1.73%542.88K$1.21B$6.24 - $21.240.00%
87Lifetime Brands, Inc.LCUT$7.61-1.16%80.59K$174.83M$2.90 - $10.170.02%
88Replimune Group, Inc.REPL$21.11+5.29%1.47M$2.00B$1.50 - $21.280.00%
89Okeanis Eco Tankers Corp.ECO$83.22+2.33%536.98K$3.64B$31.75 - $102.560.00%
90Forum Energy Technologies, Inc.FET$71.14+5.36%65.84K$800.01M$28.00 - $91.990.00%
91Noodles & CompanyNDLS$14.74-1.79%9.39K$87.95M$3.57 - $19.000.00%
92MindForge Inc.MF$10.39+13.72%58.28K$66.42M$3.80 - $22.560.00%
93Starz Entertainment Corp.STRZ$25.34+3.58%197.44K$403.16M$8.40 - $32.580.00%
94Encore Capital Group, Inc.ECPG$116.02-8.19%185.33K$2.46B$46.80 - $126.740.00%
95Trueblue, Inc.TBI$12.31-0.08%380.55K$374.92M$3.18 - $13.590.00%
96SharkNinja, Inc.SN$223.40+3.10%876.23K$31.47B$83.21 - $225.690.00%
97DHI Group, Inc.DHX$4.37-1.86%192.11K$189.94M$1.44 - $5.190.00%
98CHATHAM LODGING TRUSTCLDT$15.62+3.05%204.61K$728.93M$6.38 - $15.760.04%
99Surrozen, Inc.SRZN$30.27+3.93%51.45K$351.45M$11.51 - $37.830.00%
100Kiniksa Pharmaceuticals International, plcKNSA$93.49+5.73%301.80K$4.57B$37.02 - $98.480.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
American Well Corporation (AMWL) currently leads with a 52-week gain of 193.40% as of 2026-11-06 19:21 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.